Management of Type-2 Diabetes in Pakistan

Know Diabetes, Fight Diabetes.

The prevalence of Diabetes and complications related to it in Pakistan is high due to which Pakistan faces many health. The rate of Diabetes varies greatly around the world. Pakistan has the highest diabetes rate at 30.8%, followed by Kuwait at 24.9%, and Nauru, New Caledonia, and the Northern Mariana Islands, all at 23.4%. The study also found that the frequency of type 2 diabetes (94.49%) is higher than type 1 diabetes mellitus (5.51%).

The treatment of diabetes in Pakistan, like in many other countries, involves a combination of lifestyle changes, medication, and regular monitoring. Here are some key aspects of diabetes treatment in Pakistan:

  1. Lifestyle Modifications:
    • Diet: Patients are advised to follow a balanced diet that includes whole grains, lean proteins, fruits, and vegetables. Traditional Pakistani foods like chapati, daal, and yogurt can be part of a healthy diabetic diet when consumed in moderation.
    • Exercise: Regular physical activity is essential for managing diabetes. Patients are encouraged to engage in activities like brisk walking, cycling, or swimming. Due to cultural factors, some may prefer indoor exercises like yoga.
    • Weight Management: Maintaining a healthy weight is crucial. Healthcare providers often work with patients to set achievable weight loss goals.
  2. Medication:
    • Oral Medications: Many people with type 2 diabetes in Pakistan initially manage their condition with oral medications like metformin or sulfonylureas.
    • Insulin: Some individuals with type 1 diabetes or advanced type 2 diabetes may require insulin therapy. There are different types of insulin available, including short-acting and long-acting varieties.
  3. Blood Sugar Monitoring: Regular monitoring of blood sugar levels is important to adjust medication and lifestyle as needed. Glucometers are readily available and commonly used in Pakistan.
  4. Education: Patients are educated about the importance of managing diabetes, the role of medications, and the significance of lifestyle modifications.
  5. Access to Healthcare: Access to healthcare can vary in different regions of Pakistan. Urban areas generally have better access to healthcare facilities, while rural areas may face challenges in terms of healthcare infrastructure.
  6. Traditional Remedies: In some cases, people may also use traditional herbal remedies to manage diabetes. It’s important for healthcare providers to discuss these remedies with patients and ensure they do not interfere with prescribed medications.
  7. Regular Check-ups: Regular check-ups with healthcare providers are essential to monitor the progression of diabetes and address any complications that may arise.
  8. Complications Management: Diabetes can lead to complications like neuropathy, retinopathy, and kidney disease. Managing these complications is an important part of diabetes care.
  9. Community Support: Support groups and community-based initiatives can be valuable for individuals with diabetes, providing emotional support and education.
  10. Government Initiatives: The government of Pakistan may run healthcare programs and initiatives to improve diabetes care and awareness, especially in vulnerable populations.

It’s important to note that diabetes management is highly individualized, and treatment plans should be developed in consultation with healthcare professionals. Additionally, cultural and socioeconomic factors can influence how diabetes is managed in Pakistan, so healthcare providers should consider these factors when working with patients.

Combination Drugs used for treatment of Type-2 Diabetes

According to study the combination of two drugs i.e. sitagliptin + metformin (8.47%) is the

most prescribed followed by vildagliptin+ metformin (2.82%). The rationale for higher prescription of combination of sitagliptin and metformin is because it is recommended as an adjunct to diet as well as exercise to enhance glycemiccontrol in adults having type 2 diabetes.

The most prescribed three drugs combination was insulin + sitagliptin +metformin (5.08%) while among four drugs combination insulin + vildagliptin+ metformin + pioglitazone (0.84%)was highly prescribed. The reason for two drugs, three drugs and four drugs combination is because of conventional management of type 2 diabetes through single medication frequently fails so for better control on clinical symptoms and preventing the progression of the disease there is increase in the prescription combination drugs.

Few Examples of Combination drugs available in Pakistan used to control Diabetes are:

Poze G® Tab 30 mg/ 4 mg by
Each tablet contains 30 mg pioglitazone hydrochloride with 4 mg
glimepiride.

Pozemet ®Tab 15 mg/500 mg:

Each tablet contains 15 mg pioglitazone hydrochloride with 500mg metformin hydrochloride.

Itaglip Plus® 50mg/850mg

(Sitagliptin Phosphate + Metformin Hcl)

Galvus Met Tab 50/500mg
Vildagliptin 50mg ,Metformin 500mg